Correlation between serum cryptococcal antigen titre and meningitis in immunocompetent patients

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[Cryptococcal meningitis in an immunocompetent patient].

Cryptococcal meningitis (CM) is life threatening fungal infection of central nervous system (CNS). Although it is commonly associated with immunosuppression but rarely it can occur in immune competent patient. We report a case of 21 year old non HIV infected girl. Based on initial diagnoses of tuberculosis Bacillus meningitis (TBM), she was started on anti-tuberculosis treatment (ATT). However ...

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Cryptococcal meningitis with secondary cutaneous involvement in an immunocompetent host.

Cryptococcosis is a potentially fatal fungal disease caused by variants of Cryptococcus neoformans species.  The respiratory tract is the usual portal of entry, with a peculiar predilection to invade the central nervous system.  The skin can be secondarily involved in disseminated infection or be exceptionally involved as primary cutaneous infection by inoculation.  The disease is mostly seen i...

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Cryptococcal Meningitis

Virulence probably plays a relatively small role in the outcome of this infection: the crucial factor is the immune status of the host. The most serious infections usually develop, in fact, in patients with defective cell-mediated immunity, for example those with AIDS, organ transplantation, reticuloendothelial malignancy, corticosteroid treatment and sarcoidosis, but not in subjects with neutr...

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Cryptococcal antigen test revisited: significance for cryptococcal meningitis therapy monitoring in a tertiary chinese hospital.

For a total of 29 non-human immunodeficiency virus 1 cryptococcal meningitis cases, titer changes in the latex agglutination test before and after therapy were reviewed along with clinical manifestations, laboratory findings, and therapy regimens. The cryptococcal antigen titer decreased for every case after therapy and was correlated to fungal clearance as defined by fungus smear and/or cultur...

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Cryptococcal meningitis

© 2004 Blackwell Publishing Ltd the second most common cause of death in HIV infection after tuberculosis (French et al. 2002). Moreover, despite the availability of highly active antiretroviral therapy (HAART), it continues to pose diffi cult management questions in the industrialized world. Questions remain for physicians regarding the optimal combination of antifungal agents, duration of tre...

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ژورنال

عنوان ژورنال: Journal of Medical Microbiology

سال: 2018

ISSN: 0022-2615,1473-5644

DOI: 10.1099/jmm.0.000830